High-performance liquid chromatographic determination of ibuprofen and its major metabolites in biological fluids.
نویسندگان
چکیده
A sensitive and selective high-performance liquid-chromatographic assay for ibuprofen and its major metabolites in biological fluids is described. To ensure good chromatographic separation the drug and metabolites were run on a gradient elution system and detected with a variable wavelength detector set at 220 nm. A second, more rapid, isocratic system is also described for the detection of only ibuprofen.
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ورودعنوان ژورنال:
- Journal of chromatography
دوره 232 2 شماره
صفحات -
تاریخ انتشار 1982